Clinical Miedzo

Ikoko kwakanga kusina ma induration matsva akaonekwa muboka reNIF rakaenzaniswa ne IP. (P = 0.0150) Tsono yakaputsika yakaonekwa muboka reIP, hapana ngozi muboka reNIF.Izvo zvakagadziriswa zvinoreva kuderedza kubva kune yekutanga yeHbA1c 0.55% pavhiki 16 muboka reNFI yakanga isiri pasi uye nhamba yepamusoro kana ichienzaniswa neye 0.26% muIP boka.Kudzorwa kwe insulin neNIF kunogona kupa zvirinani kuchengetedzeka kupfuura nemajekiseni eIP, nekudzikisa mavanga eganda, indurations, kurwadziwa uye pasina njodzi yeakaputsika tsono.

Nhanganyaya:

Huwandu hwevarwere vane Type 2 chirwere cheshuga vachishandisa insulini ichiri yakaderera uye kazhinji inotangwa kunonoka.Zvinhu zvakawanda zvakaonekwa kuti zvinokanganisa kunonoka kwekushandiswa kwe insulini, kusanganisira kutya kwetsono, kusagadzikana kwepfungwa panguva yejekiseni re insulini uye kusagadzikana kwejekiseni re insulini, izvo zvose zvaive zvikonzero zvakakosha zvevarwere vakaramba kutanga insulini kurapwa.Pamusoro pezvo, kuomarara kwejekiseni senge indurations inokonzerwa nekushandisazve tsono kwenguva refu inogona kukanganisa kushanda kwe insulin kurapwa kune varwere vakatoshandisa insulin.

Iyo jekiseni ye insulin isina tsono yakagadzirirwa varwere vane chirwere cheshuga vanotya majekiseni kana kuti vanozeza kutanga insulin therapy kana ichinyatsoratidzwa.Ichi chidzidzo chine chinangwa chekuongorora kugutsikana kwevarwere uye kutevedzera nenyuchi-isina insulin injector maererano neyakajairwa insulin peni majekiseni kune varwere vane T2DM vanorapwa kwemavhiki gumi nematanhatu.

Nzira:

Huwandu hwevarwere ve427 vane T2DM vakanyoreswa mune yakawanda-center, inotarisirwa, randomized, yakavhurika-label kudzidza, uye yakaitwa randomized 1: 1 kuti vagamuchire basal insulin kana premixed insulin kuburikidza nejekiseni isina tsono kana neyakajairwa insulin peni majekiseni.

Mhedzisiro:

Muvarwere ve412 vakapedza chidzidzo, zvinoreva kuti SF-36 mibvunzo yemibvunzo yakawedzerwa zvakanyanya mune zvose zviri zviviri zvejekiseni risina tsono uye mapoka emhando dzepeni dze insulin, pasina musiyano mukuru pakati pemapoka mukuteerera.Zvisinei, zvidzidzo muboka rejekiseni risina tsono rakaratidza zvakanyanya kugutsikana kwehutano hwehutano kupfuura avo vari muboka re insulin pen mushure memavhiki e16 ekurapwa.

Pfupiso:

Hapana mutsauko wakakosha pakati pe insulin peni uye mapoka ejekiseni asina-tsono pane iyi mhedzisiro yeSF-36.

Jekiseni-isina tsono ye insulin inotungamira kune yakakwira kugutsikana kwemurwere uye nekunatsiridza kuteedzera kurapwa.

Mhedziso:

Iye jekiseni risina tsono rakavandudza hupenyu hwevarwere veT2DM uye zvakanyanya kuwedzera kugutsikana kwavo nemishonga ye insulin kana ichienzaniswa neyakajairwa insulin peni jekiseni.